Νeuromodulators are purified proteins produced by the Clostridium Botulinum bacteria. They have been used for wrinkle therapy since the early 1990's with no serious side effects documented. A small amount of neuromodulator is injected into the muscles that are responsible for creating wrinkles or undesirable facial muscle effects. The treatment is quick and somebody has to repeat the treatment 2-3times/year (the result stays longer if it's combined with 50mg tablets of zinc 1 week before and after the treatment).

Then euromodulators temporarily inactivate the muscles that produce wrinkles, thereby causing lines to disappear or diminish dramatically. It usually takes a few days after the injection to notice the wrinkle smoothing effect.

Some of the common areas treated with botox include crow's feet, frown lines, laugh lines, and forehead wrinkles; they can also be injected to weaken the muscles responsible for a "gummy smile", which can improve this appearance dramatically. Injections into muscles that lower the eyebrow or corners of the mouth can produce a form of temporary brow lift or lip lift. The last improvement is the micro-injections intra-dermally: tiny amounts of highly diluted injections decrease the sebaceous/sweat glands secretions, relax the platysma muscle and eliminate the small wrinkles around the face (Wu WT. Micro......Personal Technique and Its Clinical Effects. PRS 2015 Nov;136(5 Suppl):92S-100S). New uses for neuromodulators include reduction in sweating of hands (hyperhydrosis) and relief of headaches.