Botox received FDA approval for the treatment of chronic migraine in October 2010. It is an injectable form of botulinum toxin used for preventing migraines in adults with chronic migraine (migraines that occur on 15 or more days per month for more than 3 months, which has the features of migraine headache on at least 8 days per month).
Botox works by blocking the release of certain brain chemicals including acetylcholine and by blocking the movement of certain nerves and muscles. It is not completely known how Botox reduces headache pain and stiffness. A potential reason might be that Botox blocks nerves that send pain messages to the brain and relaxes muscles so they are less sensitive to pain.
Patients have differing levels of success with each type of treatment. Some feel reasonably better quickly, while others find their migraine symptoms completely go way.
Botox/Dysport is available in injectable form. It is recommended that this treatment be repeated every 3-4 months. In general, Botox treatment is well tolerated by the large majority of patients.
People should avoid Botox if they are allergic to any of the ingredients, have had an allergic reaction to other similar products or have a skin infection at the site where Botox will be injected. Caution should be exercised for people who have any disease that affects their muscles or nerves, those with breathing, swallowing or bleeding problems as well as those who have facial weakness such as drooping eyelids or are pregnant/breast feeding women.