Exosomes, or extracellular vesicles, represent the latest cell-free addition to the regenerative medicine toolkit. In vitro preclinical studies have demonstrated the safety and efficacy of exosomes, which vary based on source and biomanufacturing, for a myriad of potential therapeutic applications relevant to skin and soft tissue reconstruction.  Exosome technology offers an acellular, off-the-shelf, stable, therapeutic option for the modern surgical toolkit ( McGraw IT et al. Evolving role of exosphere in Plastic and Reconstructive Surgery and Dermatology. PRS GlobOpen 2024 Aug 16;12(8):e6061). There are over 200 registered studies on ClinicalTrials.gov concerning exosomes. Current literature shows promise for plastic surgery applications, including skin care and cutaneous wound healing (eg, chronic diabetic wounds), bone regeneration, flap viability, and nerve regeneration. Try our new exosomes mesotherapy treatments. 
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