Penile warts are sexually transmitted disease caused by HPV. The condition can have negative psychosocial effects on the patient and may adversely affect quality of life. Although approximately one-third of penile warts regress without treatment, active treatment is preferred to speed up clearance of the lesions, assuage fears of transmission and autoinoculation, allay emotional stress, improve cosmetic appearance, reduce social stigma associated with penile lesions and alleviate symptoms. Active treatment is low mode diathermy, laser, shaving, antiviral, and often a combination of these. The choice of the treatment method should depends on the patient’s preference and tolerability of treatment, and the number and severity of lesions. HPV vaccines prior or after to the onset of sexual activity are effective in the primary prevention of HPV infection (Leung AKC. Penile warts: an update on their evaluation and management. Drugs Comtext 2018 Dec 19;7:212563).

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