The Rise of Plastic Surgery After GLP-1 Weight Loss Drugs: Rosie O’Donnell’s Facelift and Managing Skin Laxity

Wednesday, 03 June 2026

Rosie O’Donnell’s recent revelation that she underwent a facelift after losing 50 pounds with the help of Mounjaro has highlighted a major global trend. Rapid and significant weight loss through GLP-1 receptor agonists (such as Ozempic and Mounjaro) often leaves patients dealing with severe skin laxity and a dramatic loss of facial volume—a phenomenon widely recognized as "Ozempic face."

At Opsisclinical, renowned Plastic Surgeon Dr. Ioannis Liapakis emphasizes that medical weight management or bariatric weight loss is often a two-step journey, where plastic surgery serves as the essential final step. Utilizing advanced reconstructive and aesthetic techniques, such as the high-SMAS facelift, neck lift, and facial fat grafting, Dr. Liapakis effectively restores lost structural volume and tightens saggy skin. This comprehensive approach ensures that the patient's facial features are harmoniously aligned with their new, healthier physique